Los hongos o comúnmente llamados “hongos mágicos”, han sido usados por el ser humano desde hace aproximadamente 7.000 años en diversos rituales religiosos y por un gran número de culturas a lo largo de la historia.
Para los aztecas, los hongos alucinógenos eran un alimento sagrado al que identificaban como carne o alimento de los dioses, mismos que les provocaban alucinaciones y visiones de las deidades que veneraban.
En su lengua nativa los llamaban teonanacatl, cuya etimología proviene de las voces teotl, "Dios", y nanacatl, de nacatl, "alimento".
(Encontrados 1000 y 500 a. C. en tierras mayas de Kaminaljuyú)
En estos hongos la molécula responsable de generar las alucinaciones es la psilocibina, la cual es la sustancia activa de los hongos mágicos y tiene un gran potencial para tratar adicciones y otros problemas psicológicos, como la ansiedad y la depresión.
La psilocibina tiene una efectividad del 80% como tratamiento para dejar de fumar, un 50% más que cualquier otro método conocido hasta la fecha. También se está investigando para aliviar los dolores en pacientes terminales y ahora se comprueba su efectividad para auxiliar la depresión y la ansiedad.
Un grupo de investigadores del Imperial College de Londres, liderados por el Dr. David Nutt, han realizado estudios sobre el efecto de la psilocibina en humanos. En su último trabajo, exploran los efectos de dicha molécula en pacientes diagnosticados con depresión severa y que han sido resistentes a los tratamientos convencionales para combatirla.
En el estudio se evalúa el estado de depresión de los pacientes mediante el test QIDS-SR16 (una semana antes del tratamiento con la droga), siendo uno de los test más usados para diagnosticarla, donde a valor mayor, mayor es el grado de depresión. A los pacientes se les suministró 25 mg de psilocibina, siempre con apoyo psicológico mientras duraban los efectos de la droga. Un día y 5 semanas después se les volvió a realizar el test de depresión.
Para las mediciones cerebrales, los autores realizaron variantes de la técnica de imagen por resonancia magnética funcional (fMRI por sus siglas en inglés) que les permite medir la actividad de distintas regiones cerebrales, mediante los cambios del flujo sanguíneo por minuto en dichas áreas, donde a mayor flujo, mayor es la actividad. Lo primero que encontraron fue que los pacientes tuvieron un valor menor en su índice de depresión post tratamiento con psilocibina a un día, comparado con su estado sin tratamiento, indicando la acción antidepresiva de la droga. En el caso de la amígdala cerebral, la cual se encuentra sobre-activada en depresión, se vio disminuida su función post-tratamiento con la droga, concluyendo que la psilocibina revierte los síntomas de la depresión bajando la actividad de la amígdala.
Ya sabiendo que la psilocibina tenía un efecto antidepresivo, los autores midieron la actividad antes y después del tratamiento con la droga en zonas cerebrales que sabían que están afectadas en la depresión, encontrando que la corteza prefrontal y el parahipocampo tuvieron grandes diferencias para las mediciones realizadas 5 semanas después del tratamiento con la droga, encontrando un efecto de la psilocibina a largo plazo.
Al parecer, la forma en que actúa la psilocibina en personas sanas es distinta a personas con depresión, donde en las últimas genera un efecto de “reinicio” que les estaría permitiendo volver a un estado normal o atenuado de la enfermedad.
Por otro lado, el escitalopram es un tipo de inhibidores selectivos de la recaptación de serotonina (ISRS), los medicamentos que representan la mayor parte del mercado de antidepresivos.
Al preguntarle a las personas que toman ISRS de forma crónica, a menudo dicen "Me siento embobado", dijo el Dr. Carhart-Harris, lo que significa que se suprimen tanto las emociones negativas como las positivas.
"Con la terapia con psilocibina dicen lo contrario, hablan de una liberación emocional, una reconexión y que este centro emocional clave responde mejor".
Esto podría explicarse presuntamente por lo positivo del “viaje” que les provocó el componente alucinógeno del hongo, rememorando situaciones felices y alegres, sacándolos de su estado depresivo. Más aún, este estado de reinicio puede durar como mínimo 5 semanas con sólo una dosis de la droga, siendo totalmente distinto al efecto que tienen los actuales fármacos para controlar la depresión, que requieren dosis más altas y una ingesta diaria de éstos.
Este tratamiento con Hongos requiere que literalmente las personas se enfrenten a sus demonios y liberen para entrar en una fase de reinicio.
La investigación causó un ardiente debate, ya que es la primera vez que se utiliza esta droga psicodélica para el estudio en humanos diagnosticados con depresión. Este suceso ha generado un cuestionamiento ético por parte de la sociedad sobre la acción de suministrar una sustancia ilícita en humanos por sus consecuencias indeterminadas, pero que por otro lado se revela su potencial uso medicinal, siendo siempre administrada de forma supervisada y con apoyo psicológico.
Ahora, imaginasen las grandes farmacéuticas que harán con todo su poder y su influencia cuando empiece a existir una gran demanda publicada en el tratamiento con hongos, dejando a un lado el Prozac.
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El fin de este blog es netamente contenido informativo.
Fuente tomada:
https://www.psychedelicsociety.org.au/world-first-clinical-trial-for-magic-mushrooms/
https://www.nature.com/news/2008/080703/full/news.2008.934.html
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Les personnes souffrant de narcolepsie s’endorment gГ©nГ©ralement et deviennent confuses ou somnolentes lorsqu’elles essaient de rester Г©veillГ©es. https://modafinilpascher.store/modiodal-prix/ Les mГ©decins prescrivent souvent le modafinil comme traitement Г court terme pour les personnes atteintes de narcolepsie.
Son mГ©canisme d’action n’a pas Г©tГ© entiГЁrement Г©lucidГ©, mais on pense qu’il implique la modulation des rГ©cepteurs de l’acide gamma-aminobutyrique et de la dopamine. Lorsqu’il est pris Г la dose recommandГ©e, un supplГ©ment contenant 200 mg de Modafinil est plus efficace qu’un contenant 100 mg de Modafinil. https://lemodafinil.online/modiodal-maroc/ La posologie est dГ©terminГ©e par la condition traitГ©e.
Le modafinil est un stimulant du systГЁme nerveux central, qui est thГ©orisГ© pour stimuler les voies de l’adГ©nosine dans le cerveau. https://modafinilsansordonnance.store/modafinil-achat-en-ligne/ Bien que le modafinil soit approuvГ© pour l’utilisation Г court terme de la narcolepsie et de l’apnГ©e du sommeil, son innocuitГ© pendant la grossesse est inconnue.
Le modafinil n’est pas recommandГ© chez les personnes ayant des antГ©cГ©dents de psychose ou de consommation de drogues induisant une psychose. La narcolepsie est un trouble neurologique, qui se manifeste par la narcolepsie. https://modafinilgenerique.online/acheter-modafinil-en-belgique/ Le modafinil amГ©liore la capacitГ© des gens Г rester Г©veillГ©s en aidant le cerveau Г libГ©rer de la dopamine.
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Il existe des Г©tudes suggГ©rant que le modafinil peut inhiber le DAT, ce qui pourrait permettre Г plus de dopamine de se lier aux rГ©cepteurs de la dopamine, fournissant ainsi une augmentation de la neurotransmission dopaminergique. Le modafinil est Г©galement un promГ©dicament du modafinil-monohydratГ©, qui modifie la dГ©livrance du mГ©dicament au cerveau. https://modafinilgenerique.online/provigil-generique/ Modafinil a Г©tГ© suggГ©rГ© d’agir comme une forme naturelle de cafГ©ine.
Le modafinil est un stimulant en ce sens qu’il induit l’excitation, mais il n’a pas les effets cognitifs et physiques habituels associГ©s aux stimulants comme la cocaГЇne. https://modafinilgenerique.online/modiodal-sans-ordonnance/ L’utilisation concomitante de Modafinil et d’un mГ©dicament sГ©datif peut entraГ®ner une rГ©action potentiellement mortelle appelГ©e syndrome sГ©rotoninergique.
Estudios Demuestran que Los Hongos ayudan a la Depresión – Simply Nature
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Pour la narcolepsie et les troubles du sommeil liГ©s au travail postГ©, il a Г©tГ© dГ©montrГ© que le modafinil augmente lГ©gГЁrement le temps passГ© Г dormir (tel que dГ©fini par une augmentation du sommeil Г mouvements oculaires rapides [REM]). Chez ces patients, Modafinil peut empГЄcher les substances bloquant le sommeil de les affecter dans le cerveau. https://modafinilsansordonnance.store/modafinil/ Il est utilisГ© pour le traitement de la somnolence due Г la narcolepsie, des troubles du sommeil liГ©s au travail postГ© et de l’apnГ©e obstructive du sommeil.
Il s’agit probablement d’un stimulant capable de traverser la barriГЁre hГ©mato-encГ©phalique. Le mГ©dicament est vendu sous divers noms commerciaux dans le monde, notamment Modavi-Talens, Modarrest, Modalert, Modafinil, Modate, Renaliq, Revitaliq, Stimulex et Vigora ; en 2009, il y avait 36 ​​marques diffГ©rentes disponibles aux Г‰tats-Unis. https://modafinilgenerique.store/modafinil-prix/ La structure du modafinil est similaire Г celle de l’amphГ©tamine stimulante, mais elle ne se lie pas Г un transporteur de dopamine.
Disponible sous forme de comprimГ©, de comprimГ© Г libГ©ration prolongГ©e et de vaporisateur nasal, la dose standard de modafinil (Provigil) est de 200 mg. Le modafinil a Г©tГ© approuvГ© pour la premiГЁre fois pour le traitement de la somnolence excessive dans le traitement de la narcolepsie en 1996 aux Г‰tats-Unis. https://modafinilgenerique.online/modiodal-achat/ Quelques heures aprГЁs avoir pris du modafinil, votre corps commence Г produire des niveaux naturels d’hormones qu’il utilise pour combattre l’insomnie.
Le modafinil est gГ©nГ©ralement pris environ 1 heure avant le coucher. Le modafinil est Г©galement utilisГ© dans le traitement des personnes souffrant d’autres troubles qui provoquent une somnolence diurne excessive comme la dГ©pression, certains types de douleur et l’obГ©sitГ©. https://modafinilgenerique.online/nootropique-en-vente-libre/ Le modafinil est un mГ©dicament hors brevet dont le mГ©canisme d’action n’est pas connu.
Il a des actions antagonistes sur les rГ©cepteurs muscariniques de la dopamine D2, de l’histamine H1 et de l’acГ©tylcholine. Cela rГ©duit les niveaux de cortisol et amГ©liore la synthГЁse de la sГ©rotonine. https://lemodafinil.online/alertec-vente-libre/ Le modafinil a Г©tГ© utilisГ© hors indication pour aider Г lutter contre la perte de mГ©moire, la dГ©pression et les troubles anxieux, bien que les rГ©sultats aient Г©tГ© moins satisfaisants qu’avec certains mГ©dicaments.
Le modafinil est un stimulant au niveau du SNC, mais il ne modifie pas l’Г©quilibre normal entre l’Г©veil et l’Г©quilibre des circuits cГ©rГ©braux impliquГ©s dans l’Г©veil. https://modafinilgenerique.online/acheter-modalert-200-mg-a-bas-prix-livraison-tres-rapide/ Ces rГ©sultats ont Г©tГ© enregistrГ©s dans la revue scientifique Brain Research.
Il est disponible en tant que mГ©dicament gГ©nГ©rique. Le mГ©dicament est un agent nootropique utilisГ© au Japon depuis des lustres, avec le nom de marque Noveril (de novacept) entre autres marques. https://modafinilgenerique.store/nootropique-sans-ordonnance/ Le modafinil est une molГ©cule chirale, contenant deux atomes de carbone asymГ©triques, il s’agit donc techniquement d’un Г©nantiomГЁre R, l’Г©nantiomГЁre R de l’amphГ©tamine Г©tant appelГ© dextroamphГ©tamine, l’Г©nantiomГЁre R du modafinil Г©tant appelГ© “lГ©vomodafinil”.
On pense que le modafinil a une faible affinitГ© pour les rГ©cepteurs de l’histamine (H1), les rГ©cepteurs de la dopamine (D2 et D4) et une affinitГ© substantielle pour les rГ©cepteurs de l’adГ©nosine. Le modafinil est Г©galement utilisГ© pour augmenter l’Г©veil chez les personnes atteintes de conditions dans lesquelles il est nГ©cessaire. https://modafinilsansordonnance.store/nootropique-en-france/ Bien que les mГ©dicaments WEEA soient principalement utilisГ©s pour aider les personnes souffrant de somnolence excessive ou continue associГ©e Г la privation de sommeil, ils ont Г©galement montrГ© certaines indications d’ГЄtre en mesure d’amГ©liorer la concentration et la mГ©moire chez les personnes en bonne santГ© sous des schГ©mas posologiques Г court terme.
Le modafinil est un stimulant du SNC et un agoniste sГ©lectif des rГ©cepteurs de la dopamine non amphГ©tamine D1 qui agit sur les rГ©cepteurs de la dopamine dans le cerveau et stimule l’Г©veil. Cependant, le modafinil peut ГЄtre l’une des principales causes d’abus de drogues au Royaume-Uni et a Г©tГ© liГ© Г une augmentation de la consommation problГ©matique de drogues chez les personnes utilisant le modafinil. https://modafinilgenerique.store/acheter-modalert-200-mg-a-bas-prix-livraison-tres-rapide/ Le modafinil n’est pas destinГ© aux patients ayant des antГ©cГ©dents de toxicomanie.
Assurez-vous de consulter votre fournisseur de soins de santГ© si vous prenez des mГ©dicaments sur ordonnance et que vous avez l’un des Г©lГ©ments suivants : La plus grande source d’Г©vГ©nements indГ©sirables (par rapport Г d’autres) liГ©s au modafinil signalГ©s au systГЁme britannique de notification des Г©vГ©nements indГ©sirables des mГ©dicaments et des mГ©dicaments est la catГ©gorie des effets secondaires dermatologiques. https://modafinilsansordonnance.store/nootropique-pharmacie/ Modafinil a Г©tГ© approuvГ© par la Food and Drug Administration des Г‰tats-Unis en 1998, pour le traitement de la somnolence diurne excessive.
Estudios Demuestran que Los Hongos ayudan a la Depresión – Simply Nature
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Bien que le modafinil ne soit pas connu pour crГ©er une dГ©pendance, il n’est pas recommandГ© aux personnes ayant des antГ©cГ©dents de toxicomanie. Le modafinil est gГ©nГ©ralement bien tolГ©rГ©, avec des effets secondaires possibles, notamment des maux de tГЄte, des troubles du sommeil et des nausГ©es. https://modafinilgenerique.store/modafinil-ordonnance/ Il a Г©galement Г©tГ© constatГ© que le modafinil provoque des hallucinations et peut aggraver les symptГґmes psychotiques chez les patients ayant des antГ©cГ©dents de psychose.
Au lieu d’imiter le neurotransmetteur Г©pinГ©phrine (dans l’utilisation d’amphГ©tamines), le modafinil agit en se liant Г l’adГ©nosine. Ils sont responsables des humeurs ressenties, ainsi que du besoin de sommeil et d’Г©veil, de la faim et de la libido. https://modafinilgenerique.store/modiodal-generique/ Ce mГ©dicament interagit avec l’alcool, l’acГ©taminophГЁne et certains antidГ©presseurs.
Le modafinil a une demi-vie terminale relativement longue d’environ 50 heures. https://modafinilgenerique.online/ou-trouver-modafinil/ Le nom de Modafinil est souvent Г©crit comme modafinil et modafinilo.
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